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Colitis


Colitis is an inflammatory bowel disease (IBD) that leads to the inflammation of the delicate membrane lining the colon more commonly known as the large intestine or bowel. Colitis typically causes inflammation and sores known as ulcers in the top layers of the lining of the large intestine. This disorder rarely affects the small intestine aside from the lower section that is known as the ileum. Types of IBDs that lead to the development of colitis include ulcerative colitis, which is the most common type of colitis, Crohn's colitis, diversion colitis, ischemic colitis, infectious colitis, fulminant colitis, chemical colitis, microscopic colitis, and atypical colitis.

Colitis typically affects individuals who are under 30 years of age and in rare cases it also affects individuals who are 60 years of age or older.

Causes and Risk Factors

The causes of colitis are unclear despite the fact that colitis is a very common disorder. The disease is further complicated because many contributing factors may only incite this condition in certain people. Factors that can possibly lead to colitis are:

Immune System: Ironically, the body’s own immune system can cause colitis while attempting to remove any virus or bacteria that is present in the body. The immune system sometimes overreacts and causes inflammation in the colon. In some cases, the microorganisms that invade the body cause inflammation by generating an immune response.
Heredity: This may not be a direct cause but heredity is a definite risk factor. Although the risk is not dramatically higher, individuals with a family history of colitis are more likely to develop it than others who lack such history.

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Environmental Factors: Exposure to certain toxins, specific food habits, lifestyle or weather can lead to colitis. This could be the reason that incidences of colitis are not distributed evenly among areas.
Gastrointestinal or Bariatric Surgery: People who have undergone any form of gastrointestinal or bariatric surgery such as the laproscopic bariatric surgery, the bariatric bypass surgery, the roux-en-y (RNY), the duodenal switch (DS), the biliopancreatic diversion (BD), the vertical banded gastroplasty (VBG), the sapala-wood micropuch, and adjustable gastric banding (AGB) have a higher risk in developing colitis than others who have not undergone such surgeries.
Antibiotics: Some antibiotics are known to disturb the normal functioning and the healthy bacteria population in the digestive tract which may lead to colitis.
Chronic Constipation and excessive use of Laxatives: Constipation may cause blockage in the colon by dried fecal matter which can lead to irritation. The excessive use of laxatives for inducing bowel movements enhances irritation which causes inflammation and leads to colitis.
Stress: Stress was previously believed to be a major contributing cause of colitis. However, research has revealed that stress can only worsen colitis rather than cause it.

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